![]() ![]() ![]() Proliferative lesions were present in only 2 of 23 (8.6%) coloured patients and was uncommon in all population groups. Among coloured patients, 5 of 23 (21.7%) had biopsy-proven SS-MCNS and or unbiopsied SSNS 10 (43.5%) had FSGS and 6 of 23 (26.1%) had membranous nephropathy. Only 14.4% had either biopsy-proven SS-MCNS or SSNS 32 had MCNS lesions on biopsy, but 18 were steroid resistant (SR) 67 of 236 (28.4%) had FSGS, all of whom were SR. Typical SSNS continues to be uncommon among blacks. In blacks, membranous nephropathy accounted for 40% of cases 86.2% were associated with hepatitis B virus antigens. In Indian children, 134 of 286 (46.8%) had biopsy-proven minimal change NS (MCNS) and 94.8% of these were steroid sensitive (SS) 60 (21%) had SSNS but without renal biopsy 59 (20.6%) had focal segmental glomerulosclerosis (FSGS), with only 4.4% of these being SS. We review our 20-year experience of 636 children with nephrotic syndrome (NS) in Durban, South Africa 306 (48.2%) were blacks, 307 (48.2%) Indians and 23 (3.6%) were a mixed group (coloured) 91 (14.3%) could not be categorised and were excluded from the analysis.
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